What secrets do the cancer genomes of Beckett and Sherlock, two courageous Bloodhound search and rescue dogs, hold? Despite battling different cancers, a shared genetic clue was found by Canine CGP. Their story reveals new insights into canine cancer predisposition and oncogensis, and examplifies the importance of such understanding on cancer treatment.

Bonnibel, a mixed breed girl, has had an unfortunate history with multiple cancer developed from an early age. Could Bonnibel’s repeated cancer diagnoses be due to a hereditary genetic condition, similar to Li-Fraumeni Syndrome in humans? Could this discovery lead to better health management and prevention strategies for pets?

Can advanced genome profiling redefine canine cancer diagnosis? Through the compelling cases of Daisy, Avery, Kira, and Simon, Dr. Wang demonstrated how Canine CGP delivers precise diagnostic insights that not only determine cancer types/subtypes, but also guide more effective treatments. As genomics and precision medicine paves the way for a new era in veterinary oncology, Canine CGP is helping redefine how we diagnose and care for dogs with cancer, offering new hope for patients and their families.

Lucy, a 13-year-old Golden Retriever with aggressive metastatic melanoma, was treated with palbociclib after Canine CGP revealed CDK4/6 gains, resulting in a strong and sustained response. This case also explores broader implications for immunotherapy and highlights the value of tumor-specific genomic profiling in guiding personalized and effective treatment strategies for our pets.